PD1 Knockout Engineered T Cells for Advanced Esophageal ...
Mar 16, 2017· Peripheral blood lymphocytes will be collected and Programmed cell death 1(PD1) gene will be knocked out by CRISPR Cas9 in the laboratory (PD1 Knockout T cells). The lymphocytes will be selected and expanded ex vivo and reinfused back into patients. To avoid allergic reactions, 50 mg ...